蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书p53 Rabbit pAb
Cat#:DPA03997应用：WB,IHC,ICC/IF
| Product Name: | Acetyl-p53 (Lys370) Recombinant Rabbit mAb |
| Cat No.: | RMA02939 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ICC/IF, FC, IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:100 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic acetyl-peptide corresponding to residues surrounding Lys370 of human p53 |
| Calculated Molecular Weight: | 44 kDa |
| Observed Molecular Weight: | 53 kDa |
| GenBank Accession Number: | P04637 |
| Gene ID (NCBI): | 7157 |
| Synonyms: | P53; BCC7; LFS1; TRP53 |
| Background: | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
| Category: | Primary Ab |
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