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查看说明书Recombinant Human NPM1 Protein
Cat#:TP03188应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-Nucleophosmin (Thr199) Recombinant Rabbit mAb |
| Cat No.: | RMA03003 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Thr199 of human Nucleophosmin |
| Calculated Molecular Weight: | 33 kDa |
| Observed Molecular Weight: | 38 kDa |
| GenBank Accession Number: | P06748 |
| Gene ID (NCBI): | 4869 |
| Synonyms: | B23; NPM |
| Background: | The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017] |
| Category: | Primary Ab |
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