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规格：
查看说明书MCM2 Rabbit pAb
Cat#:DPA01073应用：WB,IHC,ICC/IF,FC
| Product Name: | Phospho-MCM2 (Ser40) Recombinant Rabbit mAb |
| Cat No.: | RMA03021 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser40 of human MCM2 |
| Calculated Molecular Weight: | 102 kDa |
| Observed Molecular Weight: | 125 kDa |
| GenBank Accession Number: | P49736 |
| Gene ID (NCBI): | 4171 |
| Synonyms: | BM28; CCNL1; CDCL1; cdc19; DFNA70; D3S3194; MITOTIN |
| Background: | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012] |
| Category: | Primary Ab |
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