蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Rb Rabbit pAb
Cat#:DPA04342应用：WB,ICC/IF,IP
| Product Name: | Phospho-Rb (Ser608) Recombinant Rabbit mAb |
| Cat No.: | RMA03025 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser608 of human Rb |
| Calculated Molecular Weight: | 106 kDa |
| Observed Molecular Weight: | 110 kDa |
| GenBank Accession Number: | P06400 |
| Gene ID (NCBI): | 5925 |
| Synonyms: | RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1 |
| Background: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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