Product Name: | HDAC6 Rabbit pAb |
Cat No.: | DPA01006 |
Clonality: | Polyclonal |
Species Reactivity: | Mouse, Rat |
Tested Applications: | WB, FC, IP |
Recommended Dilution: | WB: 1:1000 FC: 1:200 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of mouse HDAC6 |
Calculated Molecular Weight: | 126 kDa |
Observed Molecular Weight: | 130 kDa |
GenBank Accession Number: | Q9Z2V5 |
Gene ID (NCBI): | 15185 |
Synonyms: | Hd6; Sfc6; Hdac5; mHDA2 |
Background: | Enables cytoskeletal protein binding activity; protein deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of peptidyl-serine phosphorylation; protein deacetylation; and protein destabilization. Acts upstream of or within several processes, including aggresome assembly; cellular protein metabolic process; and neuron projection morphogenesis. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early embryo; future midbrain; gut gland; and lung. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6). [provided by Alliance of Genome Resources, Apr 2022] |
Category: | Primary Ab |
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