蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书| Product Name: | cGAS Rabbit pAb |
| Cat No.: | DPA01025 |
| Clonality: | Polyclonal |
| Species Reactivity: | Mouse |
| Tested Applications: | WB, IP |
| Recommended Dilution: | WB: 1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse cGAS |
| Calculated Molecular Weight: | 58 kDa |
| Observed Molecular Weight: | 58 kDa |
| GenBank Accession Number: | Q8C6L5 |
| Gene ID (NCBI): | 101559 |
| Synonyms: | Mb21d1; E330016A19Rik |
| Background: | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| Category: | Primary Ab |
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