蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Bcl2 Like Protein 11 (BCL2L11)
Cat#:TP01313应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Bim Rabbit pAb |
| Cat No.: | DPA04935 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20-1:50 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Bim |
| Calculated Molecular Weight: | 22 kDa |
| Observed Molecular Weight: | 22 kDa |
| GenBank Accession Number: | O43521 |
| Gene ID (NCBI): | 10018 |
| Synonyms: | BAM; BIM; BOD |
| Background: | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013] |
| Category: | Primary Ab |
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