蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书PTF1A Rabbit pAb
Cat#:DPA04984应用：WB,IP
| Product Name: | PTF1A Rabbit pAb |
| Cat No.: | DPA04984 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of mouse PTF1A |
| Calculated Molecular Weight: | 35 kDa |
| Observed Molecular Weight: | 48 kDa |
| GenBank Accession Number: | Q9QX98 |
| Gene ID (NCBI): | 19213 |
| Synonyms: | PTF1p48; bHLHa29; PTF1-p48 |
| Background: | Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Plays a role in early and late pancreas development and differentiation. Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. Required for the formation of pancreatic acinar and ductal cells. Plays an important role in cerebellar development. Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates. |
| Category: | Primary Ab |
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