Recombinant Calpain, Small Subunit 1 (CAPNS1)
Cat#:TP01419应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Calpain S1 Rabbit pAb |
Cat No.: | DPA05007 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000-1:2000 IHC: 1:20-1:100 ICC/IF: 1:20-1:50 FC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Calpain S1 |
Calculated Molecular Weight: | 28 kDa |
Observed Molecular Weight: | 28 kDa |
GenBank Accession Number: | P04632 |
Gene ID (NCBI): | 826 |
Synonyms: | CANP; CDPS; CSS1; CANPS; CAPN4; CALPAIN4 |
Background: | This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
Category: | Primary Ab |