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Calpain S1 Rabbit pAb

Cat No.: DPA05007
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Product Name: Calpain S1 Rabbit pAb
Cat No.: DPA05007
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:1000-1:2000
IHC: 1:20-1:100
ICC/IF: 1:20-1:50
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Calpain S1
Calculated Molecular Weight: 28 kDa
Observed Molecular Weight: 28 kDa
GenBank Accession Number: P04632
Gene ID (NCBI): 826
Synonyms: CANP; CDPS; CSS1; CANPS; CAPN4; CALPAIN4
Background: This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Category: Primary Ab
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