蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书PPP4C Rabbit pAb
Cat#:DPA05039应用：WB,IHC,FC
| Product Name: | PPP4C Rabbit pAb |
| Cat No.: | DPA05039 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 FC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human PPP4C |
| Calculated Molecular Weight: | 35 kDa |
| Observed Molecular Weight: | 35 kDa |
| GenBank Accession Number: | P60510 |
| Gene ID (NCBI): | 5531 |
| Synonyms: | PP4; PPX; PP-X; PP4C; PPH3; PPP4 |
| Background: | Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. |
| Category: | Primary Ab |
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