Recombinant Human CD38 Protein
Cat#:TP01508应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | CD38 Rabbit pAb |
Cat No.: | DPA05052 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000 IHC: 1:50-1:200 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human CD38 |
Calculated Molecular Weight: | 34 kDa |
Observed Molecular Weight: | 45 kDa |
GenBank Accession Number: | P28907 |
Gene ID (NCBI): | 952 |
Synonyms: | ADPRC1; ADPRC 1 |
Background: | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Category: | Primary Ab |