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Bcl6 Rabbit pAb

Cat No.: DPA05205
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Product Name: Bcl6 Rabbit pAb
Cat No.: DPA05205
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF,IP
Recommended Dilution: WB: 1:1000
IHC: 1:20
ICC/IF: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Bcl6
Calculated Molecular Weight: 78 kDa
Observed Molecular Weight: 85 kDa
GenBank Accession Number: P41182
Gene ID (NCBI): 604
Synonyms: BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Category: Primary Ab
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