蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human mgMT Protein
Cat#:TP02967应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | MGMT Rabbit pAb |
| Cat No.: | DPA05246 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:50-1:200 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MGMT |
| Calculated Molecular Weight: | 22 kDa |
| Observed Molecular Weight: | 22 kDa |
| GenBank Accession Number: | P16455 |
| Gene ID (NCBI): | 4255 |
| Synonyms: | 6-O-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase |
| Background: | Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015] |
| Category: | Primary Ab |
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