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Annexin VII Recombinant Rabbit mAb

Cat No.: RMA01011
规格:
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  • Western blot analysis of Anti-Annexin VII antibody(RMA01011) Gel: 10%SDS-PAGE Lysate: 20 μg Primary antibody: RMA01011(Annexin VII antibody)at dilution 1:1000 Secondary antibody: Goat anti rabbit IgG (SPA10002)at 1:1000 dilution

Product Name: Annexin VII Recombinant Rabbit mAb
Cat No.: RMA01011
Clonality: Monoclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,IP
Recommended Dilution: WB,IHC,IP
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human Annexin VII
Calculated Molecular Weight: 53 kDa
Observed Molecular Weight: 51,47 kDa
GenBank Accession Number: P20073
Gene ID (NCBI): 310
Synonyms: SNX; ANX7; SYNEXIN
Background: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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