蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书pan Cadherin Rabbit pAb
Cat#:DPA03438应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | E Cadherin Recombinant Rabbit mAb |
| Cat No.: | RMA01021 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB,IHC,ICC/IF,FC,IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human E Cadherin |
| Calculated Molecular Weight: | 98 kDa |
| Observed Molecular Weight: | 80-120kDa(cleavages),135 kDa |
| GenBank Accession Number: | P12830 |
| Gene ID (NCBI): | 999 |
| Synonyms: | UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324 |
| Background: | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015] |
| Category: | Primary Ab |
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