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MCM7 Recombinant Rabbit mAb

Cat No.: RMA01246
规格:
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  • Western blot analysis of Anti-MCM7 antibody(RMA01246) Gel: 6%SDS-PAGE Lysate: 20 μg Primary antibody: RMA01246(MCM7 antibody)at dilution 1:1000 Secondary antibody: Goat anti rabbit IgG (SPA10002)at 1:1000 dilution

Product Name: MCM7 Recombinant Rabbit mAb
Cat No.: RMA01246
Clonality: Monoclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF,FC
Recommended Dilution: WB,ICC/IF,FC
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human MCM7
Calculated Molecular Weight: 81 kDa
Observed Molecular Weight: 81 kDa
GenBank Accession Number: P33993
Gene ID (NCBI): 4176
Synonyms: MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3
Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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