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alpha Actinin 4 Recombinant Rabbit mAb

Cat No.: RMA01287
规格:
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  • Western blot analysis of Anti-alpha Actinin 4 antibody(RMA01287) Gel: 6%SDS-PAGE Lysate: 20 μg Primary antibody: RMA01287(alpha Actinin 4 antibody)at dilution 1:1000 Secondary antibody: Goat anti rabbit IgG (SPA10002)at 1:1000 dilution

Product Name: alpha Actinin 4 Recombinant Rabbit mAb
Cat No.: RMA01287
Clonality: Monoclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB,IHC,ICC/IF,FC,IP
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human alpha Actinin 4
Calculated Molecular Weight: 105 kDa
Observed Molecular Weight: 105 kDa
GenBank Accession Number: O43707
Gene ID (NCBI): 81
Synonyms: FSGS; FSGS1; ACTININ-4
Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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