蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书ILF3 Rabbit pAb
Cat#:DPA03484应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | ILF3 Recombinant Rabbit mAb |
| Cat No.: | RMA01306 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,IP |
| Recommended Dilution: | WB,IHC,ICC/IF,IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human ILF3 |
| Calculated Molecular Weight: | 95 kDa |
| Observed Molecular Weight: | 95 kDa |
| GenBank Accession Number: | Q12906 |
| Gene ID (NCBI): | 3609 |
| Synonyms: | CBTF; DRBF; MMP4; MPP4; NF90; NFAR; NF110; NF90a; NF90b; NFAR2; TCP80; DRBP76; NF110b; NFAR-1; TCP11 |
| Background: | This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014] |
| Category: | Primary Ab |
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