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分子生物学
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查看说明书Recombinant Caspase 10 (CASP10)
Cat#:TP06137应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Caspase-10 Recombinant Rabbit mAb |
| Cat No.: | RMA01421 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,FC,IP |
| Recommended Dilution: | WB,IHC,FC,IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Caspase-10 |
| Calculated Molecular Weight: | 59 kDa |
| Observed Molecular Weight: | 59 kDa |
| GenBank Accession Number: | Q92851 |
| Gene ID (NCBI): | 843 |
| Synonyms: | MCH4; ALPS2; FLICE2 |
| Background: | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011] |
| Category: | Primary Ab |
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