蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书TAK1 Rabbit pAb
Cat#:DPA04107应用：WB,IHC,ICC/IF,FC
| Product Name: | TAK1 Recombinant Rabbit mAb |
| Cat No.: | RMA01443 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB,IHC,ICC/IF,FC |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human TAK1 |
| Calculated Molecular Weight: | 67 kDa |
| Observed Molecular Weight: | 78 kDa |
| GenBank Accession Number: | O43318 |
| Gene ID (NCBI): | 6885 |
| Synonyms: | CSCF; FMD2; TAK1; MEKK7; TGF1a |
| Background: | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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