KIAA1967 Rabbit pAb
Cat#:DPA04033应用:WB,IHC,ICC/IF,FC,IP
Product Name: | KIAA1967 Recombinant Rabbit mAb |
Cat No.: | RMA01468 |
Clonality: | Monoclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB,IHC,ICC/IF,FC,IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human KIAA1967 |
Calculated Molecular Weight: | 103 kDa |
Observed Molecular Weight: | 130 kDa |
GenBank Accession Number: | Q8N163 |
Gene ID (NCBI): | 57805 |
Synonyms: | DBC1; DBC-1; NET35; p30DBC; p30 DBC; KIAA1967 |
Background: | Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. |
Category: | Primary Ab |