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查看说明书Recombinant Human PSMB10 Protein
Cat#:TP03568应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | PSMB10 Recombinant Rabbit mAb |
| Cat No.: | RMA01572 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF |
| Recommended Dilution: | WB,ICC/IF |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human PSMB10 |
| Calculated Molecular Weight: | 29 kDa |
| Observed Molecular Weight: | 29 kDa |
| GenBank Accession Number: | P40306 |
| Gene ID (NCBI): | 5699 |
| Synonyms: | LMP10; MECL1; beta2i |
| Background: | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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