蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Nogo B receptor Rabbit pAb
Cat#:DPA03424应用：WB
| Product Name: | Nogo B receptor Recombinant Rabbit mAb |
| Cat No.: | RMA01710 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Nogo B receptor |
| Calculated Molecular Weight: | 33 kDa |
| Observed Molecular Weight: | 33 kDa |
| GenBank Accession Number: | Q96E22 |
| Gene ID (NCBI): | 116150 |
| Synonyms: | NgBR; MRD55; CDG1AA; C6orf68; TANGO14; MGC:7199 |
| Background: | This gene encodes a type I single transmembrane domain receptor, which is a subunit of cis-prenyltransferase, and serves as a specific receptor for the neural and cardiovascular regulator Nogo-B. The encoded protein is essential for dolichol synthesis and protein glycosylation. This gene is highly expressed in non-small cell lung carcinomas as well as estrogen receptor-alpha positive breast cancer cells where it promotes epithelial mesenchymal transition. This gene is associated with the poor prognosis of human hepatocellular carcinoma patients. Naturally occurring mutations in this gene cause a congenital disorder of glycosylation and are associated with epilepsy. A knockout of the orthologous gene in mice causes embryonic lethality before day 6.5. Pseudogenes of this gene have been defined on chromosomes 13 and X. [provided by RefSeq, May 2017] |
| Category: | Primary Ab |
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