蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书GEN1 Rabbit pAb
Cat#:DPA03317应用：WB
| Product Name: | GEN1 Recombinant Rabbit mAb |
| Cat No.: | RMA01740 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human GEN1 |
| Calculated Molecular Weight: | 103 kDa |
| Observed Molecular Weight: | 103 kDa |
| GenBank Accession Number: | Q17RS7 |
| Gene ID (NCBI): | 348654 |
| Synonyms: | Gen |
| Background: | This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016] |
| Category: | Primary Ab |
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