XPD Rabbit pAb
Cat#:DPA03315应用:WB,IHC,ICC/IF
Product Name: | XPD Recombinant Rabbit mAb |
Cat No.: | RMA01741 |
Clonality: | Monoclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF |
Recommended Dilution: | WB,IHC,ICC/IF |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human XPD |
Calculated Molecular Weight: | 87 kDa |
Observed Molecular Weight: | 80 kDa |
GenBank Accession Number: | P18074 |
Gene ID (NCBI): | 2068 |
Synonyms: | EM9; TTD; XPD; TTD1; COFS2; TFIIH |
Background: | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
Category: | Primary Ab |