SIRT1 Rabbit pAb
Cat#:DPA03151应用:WB,IHC,ICC/IF,FC,IP
Product Name: | SIRT1 Recombinant Rabbit mAb |
Cat No.: | RMA01810 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB,IHC,ICC/IF,FC,IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human SIRT1 |
Calculated Molecular Weight: | 82 kDa |
Observed Molecular Weight: | 120 kDa |
GenBank Accession Number: | Q923E4 |
Gene ID (NCBI): | 23411 |
Synonyms: | SIR2; SIR2L1; SIR2alpha |
Background: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
Category: | Primary Ab |