Histone H2A Rabbit pAb
Cat#:DPA03118应用:WB
Product Name: | Histone H2A Recombinant Rabbit mAb |
Cat No.: | RMA01829 |
Clonality: | Monoclonal |
Species Reactivity: | Saccharomyces cerevisiae |
Tested Applications: | WB |
Recommended Dilution: | WB |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of Histone H2A |
Calculated Molecular Weight: | 14 kDa |
Observed Molecular Weight: | 14 kDa |
GenBank Accession Number: | P04912 |
Synonyms: | H2A2 |
Background: | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Category: | Primary Ab |