Eukaryotic Sialic Acid Binding Ig Like Lectin 2 (CD22)
Cat#:TP08323应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | CD22 Recombinant Rabbit mAb |
Cat No.: | RMA01872 |
Clonality: | Monoclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF,IP |
Recommended Dilution: | WB,IHC,ICC/IF,IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human CD22 |
Calculated Molecular Weight: | 95 kDa |
Observed Molecular Weight: | 140 kDa |
GenBank Accession Number: | P20273 |
Gene ID (NCBI): | 933 |
Synonyms: | SIGLEC2; SIGLEC-2 |
Background: | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. |
Category: | Primary Ab |