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查看说明书Recombinant Human BAG3 Protein
Cat#:TP01292应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Bag3 Recombinant Rabbit mAb |
| Cat No.: | RMA01975 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,FC |
| Recommended Dilution: | WB,ICC/IF,FC |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Bag3 |
| Calculated Molecular Weight: | 62 kDa |
| Observed Molecular Weight: | 80 kDa |
| GenBank Accession Number: | O95817 |
| Gene ID (NCBI): | 9531 |
| Synonyms: | BIS; MFM6; BAG-3; CAIR-1 |
| Background: | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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