产品中心

MSH6 Recombinant Rabbit mAb

Cat No.: RMA02152
规格:
查看说明书
Product Name: MSH6 Recombinant Rabbit mAb
Cat No.: RMA02152
Clonality: Monoclonal
Species Reactivity: Human
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB,IHC,ICC/IF,FC,IP
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human MSH6
Calculated Molecular Weight: 163 kDa
Observed Molecular Weight: 163 kDa
GenBank Accession Number: P52701
Gene ID (NCBI): 2956
Synonyms: GTBP; HSAP; p160; GTMBP; HNPCC5
Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Category: Primary Ab
武汉天正源生物科技有限公司 版权所有 | 鄂ICP备2023000437号-1