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查看说明书Recombinant Human BCL2L1 / Bcl-XL Protein (His tag)
Cat#:TP06280应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Bcl XL Recombinant Rabbit mAb |
| Cat No.: | RMA02200 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB,IHC,ICC/IF,FC,IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Bcl-XL |
| Calculated Molecular Weight: | 26 kDa |
| Observed Molecular Weight: | 30 kDa |
| GenBank Accession Number: | Q07817 |
| Gene ID (NCBI): | 598 |
| Synonyms: | BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S |
| Background: | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015] |
| Category: | Primary Ab |
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