XRCC1 Rabbit pAb
Cat#:DPA02336应用:WB,IHC,ICC/IF
Product Name: | XRCC1 Recombinant Rabbit mAb |
Cat No.: | RMA02240 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF |
Recommended Dilution: | WB,IHC,ICC/IF |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human XRCC1 |
Calculated Molecular Weight: | 70 kDa |
Observed Molecular Weight: | 82 kDa |
GenBank Accession Number: | P18887 |
Gene ID (NCBI): | 7515 |
Synonyms: | RCC; SCAR26 |
Background: | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |