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查看说明书Recombinant Human Receptor Expressed in Lymphoid Tissues Protein
Cat#:TP05175应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | CCR7 Recombinant Rabbit mAb |
| Cat No.: | RMA02286 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB,ICC/IF,IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human CCR7 |
| Calculated Molecular Weight: | 43 kDa |
| Observed Molecular Weight: | 43 kDa |
| GenBank Accession Number: | P32248 |
| Gene ID (NCBI): | 1236 |
| Synonyms: | BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7 |
| Background: | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
| Category: | Primary Ab |
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