Recombinant Protein Phosphatase 1, Catalytic Subunit Alpha Isoform (PPP1Ca)
Cat#:TP03499应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | PP1C alpha/beta Recombinant Rabbit mAb |
Cat No.: | RMA02311 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB,IHC,ICC/IF,FC,IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human PPP1CA+PPP1CB |
Calculated Molecular Weight: | 38 kDa |
Observed Molecular Weight: | 38 kDa |
GenBank Accession Number: | P62136 |
Gene ID (NCBI): | 5499 |
Synonyms: | PP1A; PP-1A; PPP1A; PP1alpha |
Background: | The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |