Ku70 Rabbit pAb
Cat#:DPA02241应用:WB,IHC,ICC/IF
Product Name: | Ku70 Recombinant Rabbit mAb |
Cat No.: | RMA02332 |
Clonality: | Monoclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF |
Recommended Dilution: | WB,IHC,ICC/IF |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Ku70 |
Calculated Molecular Weight: | 70 kDa |
Observed Molecular Weight: | 70 kDa |
GenBank Accession Number: | P12956 |
Gene ID (NCBI): | 2547 |
Synonyms: | ML8; KU70; TLAA; CTC75; CTCBF; G22P1 |
Background: | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |