蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书GTPase HRAS Rabbit pAb
Cat#:DPA02232应用：WB,FC,IP
| Product Name: | GTPase HRAS Recombinant Rabbit mAb |
| Cat No.: | RMA02341 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,FC,IP |
| Recommended Dilution: | WB,FC,IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Ras |
| Calculated Molecular Weight: | 21 kDa |
| Observed Molecular Weight: | 21 kDa |
| GenBank Accession Number: | P01111,P01112,P01116 |
| Gene ID (NCBI): | 3265,3845,4893 |
| Synonyms: | CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1 |
| Background: | This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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