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查看说明书Recombinant Ubiquitin Like Modifier Activating Enzyme 3 (UBA3)
Cat#:TP04370应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | NEDD8 Activating Enzyme E1C Recombinant Rabbit mAb |
| Cat No.: | RMA02361 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB |
| Recommended Dilution: | WB |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human UBA3 |
| Calculated Molecular Weight: | 52 kDa |
| Observed Molecular Weight: | 52 kDa |
| GenBank Accession Number: | Q8TBC4 |
| Gene ID (NCBI): | 9039 |
| Synonyms: | NAE2; UBE1C; hUBA3 |
| Background: | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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