Recombinant Ataxin 3 (ATXN3)
Cat#:TP01258应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Ataxin 3 Recombinant Rabbit mAb |
Cat No.: | RMA02401 |
Clonality: | Monoclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB |
Recommended Dilution: | WB |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Ataxin 3 |
Calculated Molecular Weight: | 42 kDa |
Observed Molecular Weight: | 42 kDa |
GenBank Accession Number: | P54252 |
Gene ID (NCBI): | 4287 |
Synonyms: | AT3; JOS; MJD; ATX3; MJD1; SCA3 |
Background: | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016] |
Category: | Primary Ab |