蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书KIFAP3 Rabbit pAb
Cat#:DPA02192应用：WB,IHC,ICC/IF
| Product Name: | KIFAP3 Recombinant Rabbit mAb |
| Cat No.: | RMA02471 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB,IHC,ICC/IF |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human KIFAP3 |
| Calculated Molecular Weight: | 91 kDa |
| Observed Molecular Weight: | 91 kDa |
| GenBank Accession Number: | Q92845 |
| Gene ID (NCBI): | 22920 |
| Synonyms: | FLA3; KAP3; SMAP; KAP-1; KAP-3; Smg-GDS; dJ190I16.1 |
| Background: | The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| Category: | Primary Ab |
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