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Proteasome 20S LMP2 Recombinant Rabbit mAb

Cat No.: RMA02531
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Product Name: Proteasome 20S LMP2 Recombinant Rabbit mAb
Cat No.: RMA02531
Clonality: Monoclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,FC
Recommended Dilution: WB,ICC/IF,FC
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Proteasome 20S LMP2
Calculated Molecular Weight: 23 kDa
Observed Molecular Weight: 23 kDa
GenBank Accession Number: P28065
Gene ID (NCBI): 5698
Synonyms: LMP2; PSMB6i; RING12; beta1i
Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. [provided by RefSeq, Mar 2010]
Category: Primary Ab
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