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Prealbumin Recombinant Rabbit mAb

Cat No.: RMA02576
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Product Name: Prealbumin Recombinant Rabbit mAb
Cat No.: RMA02576
Clonality: Monoclonal
Species Reactivity: Human
Tested Applications: WB,IHC,IP
Recommended Dilution: WB,IHC,IP
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Prealbumin
Calculated Molecular Weight: 16 kDa
Observed Molecular Weight: 16 kDa
GenBank Accession Number: P02766
Gene ID (NCBI): 7276
Synonyms: CTS; ATTR; CTS1; PALB; TBPA; HEL111; HsT2651
Background: This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]
Category: Primary Ab
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