CD11b Rabbit pAb
Cat#:DPA01737应用:WB,FC
Product Name: | CD11b Recombinant Rabbit mAb |
Cat No.: | RMA02581 |
Clonality: | Monoclonal |
Species Reactivity: | Mouse |
Tested Applications: | WB,ICC/IF,FC,IP |
Recommended Dilution: | WB,ICC/IF,FC,IP |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of mouse CD11b |
Calculated Molecular Weight: | 128 kDa |
Observed Molecular Weight: | 170 kDa |
GenBank Accession Number: | P05555 |
Gene ID (NCBI): | 16409 |
Synonyms: | CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik |
Background: | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
Category: | Primary Ab |