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查看说明书Recombinant Human Proprotein Convertase Subtilisin/Kexin Type 9/PCSK9 Protein(C-6His/HA/AVI)
Cat#:TP05982应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | PCSK9 Recombinant Rabbit mAb |
| Cat No.: | RMA02708 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB, IP |
| Recommended Dilution: | WB, IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human PCSK9 |
| Calculated Molecular Weight: | 74 kDa |
| Observed Molecular Weight: | 65,80 kDa |
| GenBank Accession Number: | Q8NBP7 |
| Gene ID (NCBI): | 255738 |
| Synonyms: | FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3 |
| Background: | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| Category: | Primary Ab |
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