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查看说明书Recombinant Stress Induced Phosphoprotein 1 (STIP1)
Cat#:TP04060应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | STIP1 Recombinant Rabbit mAb |
| Cat No.: | RMA02712 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC, ICC/IF, FC, IP |
| Recommended Dilution: | WB, IHC, ICC/IF, FC, IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human STIP1 |
| Calculated Molecular Weight: | 63 kDa |
| Observed Molecular Weight: | 63 kDa |
| GenBank Accession Number: | P31948 |
| Gene ID (NCBI): | 10963 |
| Synonyms: | HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521 |
| Background: | STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009] |
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