产品中心

ERCC1 Recombinant Rabbit mAb

Cat No.: RMA02735
规格:
查看说明书
  • Western blot analysis of Anti-ERCC1 antibody(RMA02735) Gel: 15%SDS-PAGE Lysate: 20 μg Primary antibody: RMA02735(ERCC1 antibody)at dilution 1:1000 Secondary antibody: Goat anti rabbit IgG (SPA10002)at 1:1000 dilution

Product Name: ERCC1 Recombinant Rabbit mAb
Cat No.: RMA02735
Clonality: Monoclonal
Species Reactivity: Human, Mouse
Tested Applications: WB, IHC, ICC/IF, FC
Recommended Dilution: WB, IHC, ICC/IF, FC
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human ERCC1
Calculated Molecular Weight: 33 kDa
Observed Molecular Weight: 39 kDa
GenBank Accession Number: P07992
Gene ID (NCBI): 2067
Synonyms: UV20; COFS4; RAD10
Background: The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]
Category: Primary Ab
武汉天正源生物科技有限公司 版权所有 | 鄂ICP备2023000437号-1