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分子生物学
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查看说明书Recombinant Human DYNLL1 Protein
Cat#:TP01944应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | DYNLL1 Recombinant Rabbit mAb |
| Cat No.: | RMA02759 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC, ICC/IF, FC, IP |
| Recommended Dilution: | WB, IHC, ICC/IF, FC, IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human DYNLL1 |
| Calculated Molecular Weight: | 10 kDa |
| Observed Molecular Weight: | 10 kDa |
| GenBank Accession Number: | P63167 |
| Gene ID (NCBI): | 8655 |
| Synonyms: | LC8; PIN; DLC1; DLC8; LC8a; DNCL1; hdlc1; DNCLC1 |
| Background: | Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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