蛋白
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检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human GAD1 Protein
Cat#:TP02174应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | GAD67 Recombinant Rabbit mAb |
| Cat No.: | RMA02856 |
| Clonality: | Monoclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IP |
| Recommended Dilution: | WB, IP |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human GAD67 |
| Calculated Molecular Weight: | 67 kDa |
| Observed Molecular Weight: | 67 kDa |
| GenBank Accession Number: | Q99259 |
| Gene ID (NCBI): | 2571 |
| Synonyms: | GAD; SCP; CPSQ1 |
| Background: | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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