Recombinant Human Histone H3.1 / HIST1H3A / H3FA Protein
Cat#:TP06641应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | DiMethyl-Histone H3 (Lys4) Rabbit pAb |
Cat No.: | DPA05305 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF,ChIP |
Recommended Dilution: | WB: 1:1000 IHC: 1:1000 ICC/IF: 1:200 ChIP: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic methyl-peptide corresponding to residues surrounding Lys4 of human Histone H3 |
Calculated Molecular Weight: | 15 kDa |
Observed Molecular Weight: | 17 kDa |
GenBank Accession Number: | P68431 |
Gene ID (NCBI): | 8356 |
Synonyms: | H3K4me; H3 histone; HIST1H3A; Histone cluster 1; H3a |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
Category: | Primary Ab |