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检测试剂盒
辅助试剂
分子生物学
规格：
查看说明书Recombinant Human ERN1 / IRE1 Protein (aa 465-977, His & GST tag)
Cat#:TP08369应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-IRE1 (Ser724) Rabbit pAb |
| Cat No.: | DPA05328 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000-1:5000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser724 of human IRE1 |
| Calculated Molecular Weight: | 110 kDa |
| Observed Molecular Weight: | 110 kDa |
| GenBank Accession Number: | O75460 |
| Gene ID (NCBI): | 10595 |
| Synonyms: | IRE1b; IRE2p; hIRE2p; IRE1-BETA |
| Background: | Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis. |
| Category: | Primary Ab |
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