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查看说明书Recombinant Human SIRT1 Protein
Cat#:TP03943应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Phospho-SIRT1 (Ser47) Rabbit pAb |
| Cat No.: | DPA05348 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser47 of human SIRT1 |
| Calculated Molecular Weight: | 82 kDa |
| Observed Molecular Weight: | 120 kDa |
| GenBank Accession Number: | Q96EB6 |
| Gene ID (NCBI): | 23411 |
| Synonyms: | SIR2; SIR2L1; SIR2alpha |
| Background: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
| Category: | Primary Ab |
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